BDBM50089199 3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxyamide::CHEMBL78001

SMILES CCCCC(CC(=O)NO)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=YPLGVMIJHPJLRA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50089199   

TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  4.50E+5nMAssay Description:Inhibitory activity against Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against endopeptidase enzyme (NEP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed