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BDBM50089206 3-Benzenesulfonyl-3-benzo[1,3]dioxol-5-yl-N-hydroxy-propionamide::CHEMBL78297

SMILES: ONC(=O)CC(c1ccc2OCOc2c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=WNJIUSSQZBGXRU-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089206   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptide deformylase


(Escherichia coli)
BDBM50089206
PNG
(3-Benzenesulfonyl-3-benzo[1,3]dioxol-5-yl-N-hydrox...)
Show SMILES ONC(=O)CC(c1ccc2OCOc2c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1/C16H15NO6S/c18-16(17-19)9-15(24(20,21)12-4-2-1-3-5-12)11-6-7-13-14(8-11)23-10-22-13/h1-8,15,19H,9-10H2,(H,17,18)
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



F. Hoffmann-La Roche Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.


J Med Chem 43: 2324-31 (2000)


Article DOI: 10.1021/jm000018k
BindingDB Entry DOI: 10.7270/Q2QF8TJR
More data for this
Ligand-Target Pair