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BDBM50089241 CHEMBL3577859

SMILES: CC(C)n1c2nc(ncc2ccc1=O)N1CCC(CO)CC1

InChI Key: InChIKey=PZCOVRMQVKTFHC-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089241   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (Human))
BDBM50089241
PNG
(CHEMBL3577859)
Show SMILES CC(C)n1c2nc(ncc2ccc1=O)N1CCC(CO)CC1
Show InChI InChI=1S/C16H22N4O2/c1-11(2)20-14(22)4-3-13-9-17-16(18-15(13)20)19-7-5-12(10-21)6-8-19/h3-4,9,11-12,21H,5-8,10H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



Translational Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assay


ACS Med Chem Lett 6: 413-8 (2015)


Article DOI: 10.1021/ml500474d
BindingDB Entry DOI: 10.7270/Q2KH0Q2N
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 8


(Homo sapiens (Human))
BDBM50089241
PNG
(CHEMBL3577859)
Show SMILES CC(C)n1c2nc(ncc2ccc1=O)N1CCC(CO)CC1
Show InChI InChI=1S/C16H22N4O2/c1-11(2)20-14(22)4-3-13-9-17-16(18-15(13)20)19-7-5-12(10-21)6-8-19/h3-4,9,11-12,21H,5-8,10H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Translational Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assay


ACS Med Chem Lett 6: 413-8 (2015)


Article DOI: 10.1021/ml500474d
BindingDB Entry DOI: 10.7270/Q2KH0Q2N
More data for this
Ligand-Target Pair