BDBM50089337 CHEMBL3577940
SMILES CC(C)N(C)[C@@H]1CC[C@H](NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)[C@H](CCc2ccccc2)C1
InChI Key InChIKey=AQTIPNCIMOFYSH-SDUSCBPUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50089337
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by FLIPR based flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMT: 2°CAssay Description:Inhibition of [125I]hMCP1 binding to CCR2 in human PBMC incubated for 30 mins at room temperatureMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair