BDBM50089436 CHEMBL3578015

SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCNC(=O)CCNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1cccc2ccccc12)NC(=O)[C@@H](N)CCCCN)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

InChI Key

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50089436   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataEC50:  100nMAssay Description:Inverse agonist activity at human GHSR1a receptor expressed in COS-7 cells assessed as inositol phosphate accumulation after 2 hrs by anion exchange ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human neuropeptide Y Y2 receptor expressed in COS-7 cells cotransfected with chimeric Gi/q protein assessed as inositol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataIC50:  126nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataEC50:  100nMAssay Description:Inverse agonist activity at human GHSR1a receptor expressed in COS-7 cells assessed as inositol phosphate accumulation after 2 hrs by anion exchange ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human neuropeptide Y Y2 receptor expressed in COS-7 cells cotransfected with chimeric Gi/q protein assessed as inositol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataIC50:  126nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50089436(CHEMBL3578015)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed