BDBM50089537 5-{[4-(3,3-Dimethyl-but-1-ynyl)-benzyl]-methyl-amino}-3,4-dihydro-1H-quinolin-2-one::CHEMBL443517

SMILES CN(Cc1ccc(cc1)C#CC(C)(C)C)c1cccc2NC(=O)CCc12

InChI Key InChIKey=RCIXWNJNPMQKFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089537   

TargetChitin synthase 1/2/3(Candida albicans)TBA
LigandPNGBDBM50089537(5-{[4-(3,3-Dimethyl-but-1-ynyl)-benzyl]-methyl-ami...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of Candida albicans chitin synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChitin synthase 1(Candida albicans)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089537(5-{[4-(3,3-Dimethyl-but-1-ynyl)-benzyl]-methyl-ami...)
Affinity DataIC50:  7.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed