BDBM50090122 CHEMBL3581545::US9216988, 116
SMILES CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)c2cc(F)cc(F)c2)c(F)c1
InChI Key InChIKey=LHPJLIOBTGASHY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50090122
Affinity DataIC50: 49nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added
to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash
bu...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed as activa...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Displacement of [3H2]-25-hydroxycholesterol from N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial express...More data for this Ligand-Target Pair