BDBM50090131 7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydroxy-pentyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid::CHEMBL289373

SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1F

InChI Key InChIKey=ZGXUCMQIVLIZTA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090131   

TargetProstaglandin F2-alpha receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090131(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]PGF-2 from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090131(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Affinity DataIC50: 3.10E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]PGE-2 from human Prostaglandin E receptor EP1 isolated from CHO-KI cells (% of control ligand,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090131(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone<20%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090131(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed