BDBM50090276 2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-2-hydroxy-1-phenyl-ethyl)-amide::CHEMBL41981

SMILES NC(=N)NCCCC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@H](CO)c1ccccc1

InChI Key InChIKey=HMBAZAWAYQBQCT-XMMISQBUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090276   

TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090276(2-Diphenylacetylamino-5-guanidino-pentanoic acid (...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of binding of [3H]-propionyl-NPY (1 nM) to Neuropeptide Y receptor type 5 in HEC-1-B cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090276(2-Diphenylacetylamino-5-guanidino-pentanoic acid (...)
Affinity DataIC50:  184nMAssay Description:NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090276(2-Diphenylacetylamino-5-guanidino-pentanoic acid (...)
Affinity DataIC50:  5.40E+5nMAssay Description:Inhibition of binding of [3H]-propionyl-NPY (1 nM) to Neuropeptide Y receptor type 2 in SMS-KAN cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090276(2-Diphenylacetylamino-5-guanidino-pentanoic acid (...)
Affinity DataIC50:  900nMAssay Description:NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed