BDBM50090281 2-Diphenylacetylamino-5-guanidino-pentanoic acid [1-(4-hydroxy-phenyl)-ethyl]-amide::CHEMBL288355

SMILES CC(NC(=O)C(CCCNC(N)=N)NC(=O)C(c1ccccc1)c1ccccc1)c1ccc(O)cc1

InChI Key InChIKey=AOUQZUZEYSDMEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090281   

TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090281(2-Diphenylacetylamino-5-guanidino-pentanoic acid [...)
Affinity DataIC50: 19nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 1 in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090281(2-Diphenylacetylamino-5-guanidino-pentanoic acid [...)
Affinity DataIC50: 60nMAssay Description:NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090281(2-Diphenylacetylamino-5-guanidino-pentanoic acid [...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 5 in HEC-1-B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50090281(2-Diphenylacetylamino-5-guanidino-pentanoic acid [...)
Affinity DataIC50: 5.75E+5nMAssay Description:Inhibition of binding of [3H]propionyl-NPY (1 nM) to Neuropeptide Y receptor type 2 in SMS-KAN cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed