BDBM50090315 4-Phenyl-1-[3-(2-p-tolyl-acetylamino)-propyl]-piperidine-4-carboxylic acid methyl ester::CHEMBL43799

SMILES COC(=O)C1(CCN(CCCNC(=O)Cc2ccc(C)cc2)CC1)c1ccccc1

InChI Key InChIKey=RLWVXIUJPCHTSK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50090315   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090315(4-Phenyl-1-[3-(2-p-tolyl-acetylamino)-propyl]-pipe...)
Affinity DataKi:  74nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090315(4-Phenyl-1-[3-(2-p-tolyl-acetylamino)-propyl]-pipe...)
Affinity DataKi:  74nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090315(4-Phenyl-1-[3-(2-p-tolyl-acetylamino)-propyl]-pipe...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090315(4-Phenyl-1-[3-(2-p-tolyl-acetylamino)-propyl]-pipe...)
Affinity DataKi: >3.00E+3nMAssay Description:In vitro binding affinity towards cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090315(4-Phenyl-1-[3-(2-p-tolyl-acetylamino)-propyl]-pipe...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090315(4-Phenyl-1-[3-(2-p-tolyl-acetylamino)-propyl]-pipe...)
Affinity DataKi:  3.40E+3nMAssay Description:In vitro binding affinity towards cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed