Found 4 hits for monomerid = 50090346 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50090346
(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)Show SMILES COc1ccc(Oc2cccc(c2)C(CC(=O)NO)S(=O)(=O)c2ccc(OC)c(OC3CCCC3)c2)cc1 Show InChI InChI=1S/C28H31NO8S/c1-34-20-10-12-22(13-11-20)36-23-9-5-6-19(16-23)27(18-28(30)29-31)38(32,33)24-14-15-25(35-2)26(17-24)37-21-7-3-4-8-21/h5-6,9-17,21,27,31H,3-4,7-8,18H2,1-2H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Inhibitory activity against recombinant matrix metalloproteinase-1 |
Bioorg Med Chem Lett 10: 1637-40 (2000)
Article DOI: 10.1016/s0960-894x(00)00285-7
BindingDB Entry DOI: 10.7270/Q20G3JDK |
More data for this
Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50090346
(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)Show SMILES COc1ccc(Oc2cccc(c2)C(CC(=O)NO)S(=O)(=O)c2ccc(OC)c(OC3CCCC3)c2)cc1 Show InChI InChI=1S/C28H31NO8S/c1-34-20-10-12-22(13-11-20)36-23-9-5-6-19(16-23)27(18-28(30)29-31)38(32,33)24-14-15-25(35-2)26(17-24)37-21-7-3-4-8-21/h5-6,9-17,21,27,31H,3-4,7-8,18H2,1-2H3,(H,29,30) | PDB
Reactome pathway
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenate |
Bioorg Med Chem Lett 10: 1637-40 (2000)
Article DOI: 10.1016/s0960-894x(00)00285-7
BindingDB Entry DOI: 10.7270/Q20G3JDK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50090346
(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)Show SMILES COc1ccc(Oc2cccc(c2)C(CC(=O)NO)S(=O)(=O)c2ccc(OC)c(OC3CCCC3)c2)cc1 Show InChI InChI=1S/C28H31NO8S/c1-34-20-10-12-22(13-11-20)36-23-9-5-6-19(16-23)27(18-28(30)29-31)38(32,33)24-14-15-25(35-2)26(17-24)37-21-7-3-4-8-21/h5-6,9-17,21,27,31H,3-4,7-8,18H2,1-2H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Inhibitory activity against recombinant matrix metalloproteinase-2 |
Bioorg Med Chem Lett 10: 1637-40 (2000)
Article DOI: 10.1016/s0960-894x(00)00285-7
BindingDB Entry DOI: 10.7270/Q20G3JDK |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50090346
(3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-N-h...)Show SMILES COc1ccc(Oc2cccc(c2)C(CC(=O)NO)S(=O)(=O)c2ccc(OC)c(OC3CCCC3)c2)cc1 Show InChI InChI=1S/C28H31NO8S/c1-34-20-10-12-22(13-11-20)36-23-9-5-6-19(16-23)27(18-28(30)29-31)38(32,33)24-14-15-25(35-2)26(17-24)37-21-7-3-4-8-21/h5-6,9-17,21,27,31H,3-4,7-8,18H2,1-2H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone-Poulenc Rorer
Curated by ChEMBL
| Assay Description
Inhibitory activity against recombinant matrix metalloproteinase-3 |
Bioorg Med Chem Lett 10: 1637-40 (2000)
Article DOI: 10.1016/s0960-894x(00)00285-7
BindingDB Entry DOI: 10.7270/Q20G3JDK |
More data for this
Ligand-Target Pair | |
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