BDBM50090354 3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-(4-phenoxy-phenyl)-pentanoic acid hydroxyamide::CHEMBL43256

SMILES: COc1ccc(cc1OC1CCCC1)S(=O)(=O)C(CCc1ccc(Oc2ccccc2)cc1)CC(=O)NO

InChI Key: InChIKey=OFWLISQOQVGMBV-UHFFFAOYNA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50090354 (3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-(...) Show SMILES COc1ccc(cc1OC1CCCC1)S(=O)(=O)C(CCc1ccc(Oc2ccccc2)cc1)CC(=O)NO Show InChI InChI=1/C29H33NO7S/c1-35-27-18-17-25(19-28(27)37-23-9-5-6-10-23)38(33,34)26(20-29(31)30-32)16-13-21-11-14-24(15-12-21)36-22-7-3-2-4-8-22/h2-4,7-8,11-12,14-15,17-19,23,26,32H,5-6,9-10,13,16,20H2,1H3,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against recombinant matrix metalloproteinase-3				Bioorg Med Chem Lett 10: 1637-40 (2000) Article DOI: 10.1016/s0960-894x(00)00285-7 BindingDB Entry DOI: 10.7270/Q20G3JDK
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50090354 (3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-(...) Show SMILES COc1ccc(cc1OC1CCCC1)S(=O)(=O)C(CCc1ccc(Oc2ccccc2)cc1)CC(=O)NO Show InChI InChI=1/C29H33NO7S/c1-35-27-18-17-25(19-28(27)37-23-9-5-6-10-23)38(33,34)26(20-29(31)30-32)16-13-21-11-14-24(15-12-21)36-22-7-3-2-4-8-22/h2-4,7-8,11-12,14-15,17-19,23,26,32H,5-6,9-10,13,16,20H2,1H3,(H,30,31)	PDB GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Rorer Curated by ChEMBL					Assay Description Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenate				Bioorg Med Chem Lett 10: 1637-40 (2000) Article DOI: 10.1016/s0960-894x(00)00285-7 BindingDB Entry DOI: 10.7270/Q20G3JDK
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50090354 (3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-(...) Show SMILES COc1ccc(cc1OC1CCCC1)S(=O)(=O)C(CCc1ccc(Oc2ccccc2)cc1)CC(=O)NO Show InChI InChI=1/C29H33NO7S/c1-35-27-18-17-25(19-28(27)37-23-9-5-6-10-23)38(33,34)26(20-29(31)30-32)16-13-21-11-14-24(15-12-21)36-22-7-3-2-4-8-22/h2-4,7-8,11-12,14-15,17-19,23,26,32H,5-6,9-10,13,16,20H2,1H3,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against recombinant matrix metalloproteinase-1				Bioorg Med Chem Lett 10: 1637-40 (2000) Article DOI: 10.1016/s0960-894x(00)00285-7 BindingDB Entry DOI: 10.7270/Q20G3JDK
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50090354 (3-(3-Cyclopentyloxy-4-methoxy-benzenesulfonyl)-5-(...) Show SMILES COc1ccc(cc1OC1CCCC1)S(=O)(=O)C(CCc1ccc(Oc2ccccc2)cc1)CC(=O)NO Show InChI InChI=1/C29H33NO7S/c1-35-27-18-17-25(19-28(27)37-23-9-5-6-10-23)38(33,34)26(20-29(31)30-32)16-13-21-11-14-24(15-12-21)36-22-7-3-2-4-8-22/h2-4,7-8,11-12,14-15,17-19,23,26,32H,5-6,9-10,13,16,20H2,1H3,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against recombinant matrix metalloproteinase-2				Bioorg Med Chem Lett 10: 1637-40 (2000) Article DOI: 10.1016/s0960-894x(00)00285-7 BindingDB Entry DOI: 10.7270/Q20G3JDK
					More data for this Ligand-Target Pair