BDBM50090380 3-(3,4-Dimethoxy-benzenesulfonyl)-N-hydroxy-3-phenyl-propionamide::CHEMBL42739

SMILES COc1ccc(cc1OC)S(=O)(=O)C(CC(=O)NO)c1ccccc1

InChI Key InChIKey=PLJQSRJZKINNOL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090380   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090380(3-(3,4-Dimethoxy-benzenesulfonyl)-N-hydroxy-3-phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090380(3-(3,4-Dimethoxy-benzenesulfonyl)-N-hydroxy-3-phen...)
Affinity DataIC50:  580nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090380(3-(3,4-Dimethoxy-benzenesulfonyl)-N-hydroxy-3-phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090380(3-(3,4-Dimethoxy-benzenesulfonyl)-N-hydroxy-3-phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed