BDBM50090493 4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid methyl ester::CHEMBL46413

SMILES COC(=O)C1CN(C)CCC1c1ccc(Cl)cc1

InChI Key InChIKey=GDFVYUDIAQQDTA-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50090493   

TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090493(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  90nMAssay Description:Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090493(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  228nMAssay Description:Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090493(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  233nMAssay Description:Inhibition of high affinity uptake by the dopamine transporter from rat synaptosomal nerve endings by using [3H]DA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090493(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  248nMAssay Description:Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090493(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  252nMAssay Description:Inhibition of high affinity uptake by the norepinephrine transporter from rat synaptosomal nerve endings by using [3H]NE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090493(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  5.88E+3nMAssay Description:Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090493(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  8.49E+3nMAssay Description:Inhibition of high affinity uptake by the serotonin transporter (5-HT) from rat synaptosomal nerve endings by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed