BDBM50090776 CHEMBL97467::[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 3,5-dimethyl-phenyl ester

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)Oc3cc(C)cc(C)c3)c2c1

InChI Key InChIKey=DKTMSWZWAXACFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090776   

TargetProstaglandin G/H synthase 2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50090776([1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (66 nM) using [14C]-AA (50 uM) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50090776([1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 6.60E+4nMAssay Description:In vitro inhibitory activity against ovine Prostaglandin G/H synthase 1 (44 nM) using [14C]AA (50 uM) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed