BDBM50091041 CHEMBL3582116

SMILES Cc1ncn(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCc12

InChI Key InChIKey=UEXZLIHDHZAEEC-KLOZGLDBSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091041   

TargetGlucocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50091041(CHEMBL3582116)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]-dexamethasone from cytosolic fraction of human recombinant glucocorticoid receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50091041(CHEMBL3582116)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at human glucocorticoid receptor transfected in CHOK1 cells assessed as inhibition of dexamethasone-induced receptor transcriptio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed