BDBM50091313 CHEMBL3582214
SMILES N#Cc1cc2c(cn1)[nH]c1ncc(cc21)-c1nc(CN2CCCCC2)cs1
InChI Key InChIKey=FKFWKGGBTFGKFN-DKYXIQLCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50091313
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
Affinity DataEC50: 658nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human acetylcholine esterase by horseradish peroxidase-coupled fluorescence assayMore data for this Ligand-Target Pair