BDBM50091313 CHEMBL3582214

SMILES N#Cc1cc2c(cn1)[nH]c1ncc(cc21)-c1nc(CN2CCCCC2)cs1

InChI Key InChIKey=FKFWKGGBTFGKFN-DKYXIQLCSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091313   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091313(CHEMBL3582214)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091313(CHEMBL3582214)
Affinity DataEC50:  658nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091313(CHEMBL3582214)
Affinity DataIC50:  18nMAssay Description:Inhibition of human acetylcholine esterase by horseradish peroxidase-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed