BDBM50091532 4-Amino-N-(4-iodo-5-methyl-isoxazol-3-yl)-benzenesulfonamide::CHEMBL298976

SMILES Cc1onc(NS(=O)(=O)c2ccc(N)cc2)c1I

InChI Key InChIKey=FCLGWHGVNGNUQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091532   

TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091532(4-Amino-N-(4-iodo-5-methyl-isoxazol-3-yl)-benzenes...)
Affinity DataIC50:  1.10E+4nMAssay Description:Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091532(4-Amino-N-(4-iodo-5-methyl-isoxazol-3-yl)-benzenes...)
Affinity DataIC50: >1.00E+6nMAssay Description:Binding affinity towards displacement of [125 I] ET-3 from COS-7 cells transfected with porcine Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed