BDBM50091726 (S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL262002

SMILES COCC1=C([C@@H](N(C(=O)N[C@@H]2CC[C@H](C2)N2CCC(CC2)c2ccccc2C#N)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC

InChI Key InChIKey=JWAHBXONODWUEH-SGQNLQFHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091726   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091726((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091726((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor stably expressed in HL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091726((S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-y...)
Affinity DataKi:  91nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor stably expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed