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BDBM50091818 CHEMBL61743::Isoquinolin-3-ylamine::uPa_46

SMILES: c1ccc2cnc(cc2c1)N

InChI Key: InChIKey=VYCKDIRCVDCQAE-UHFFFAOYSA-N

Data: 2 KI 2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091818
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, inducible (Human)	BDBM50091818 (CHEMBL61743 \| uPa_46 \| Isoquinolin-3-ylamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50091818 (CHEMBL61743 \| uPa_46 \| Isoquinolin-3-ylamine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.76E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Human)	BDBM50091818 (CHEMBL61743 \| uPa_46 \| Isoquinolin-3-ylamine) Show SMILES Show InChI	GoogleScholar	UniChem		>3.00E+4	>-6.17	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator [179-424,C299A,N323Q] (Human)	BDBM50091818 (CHEMBL61743 \| uPa_46 \| Isoquinolin-3-ylamine) Show SMILES Show InChI	GoogleScholar	UniChem		>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair