BDBM50092043 1-(2,4-Dichloro-phenyl)-4-((1S,2S)-2-phenyl-cyclopropylmethyl)-piperazine::CHEMBL1204116::CHEMBL302075

SMILES Clc1ccc(N2CCN(C[C@H]3C[C@@H]3c3ccccc3)CC2)c(Cl)c1

InChI Key InChIKey=AOSAPZYJOHCROI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092043   

TargetD(4) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50092043(CHEMBL302075 | CHEMBL1204116 | 1-(2,4-Dichloro-phe...)
Affinity DataKi:  5nMAssay Description:Binding affinity at human Dopamine receptor D4 by [3H]- YM 09151 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50092043(CHEMBL302075 | CHEMBL1204116 | 1-(2,4-Dichloro-phe...)
Affinity DataIC50: 9nMAssay Description:Binding affinity to dopamine receptor D4 cloned from human, using [3H]- YM09151 as competitive ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50092043(CHEMBL302075 | CHEMBL1204116 | 1-(2,4-Dichloro-phe...)
Affinity DataIC50: 65nMAssay Description:Binding affinity to dopamine receptor D2 cloned from human, using [3H]- YM09151 as competitive ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50092043(CHEMBL302075 | CHEMBL1204116 | 1-(2,4-Dichloro-phe...)
Affinity DataKi:  93nMAssay Description:Binding affinity at human Dopamine receptor D2 by [3H]- YM 09151 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed