BDBM50092099 3-Methyl-4-[4-(4-pyridin-4-yl-piperazin-1-yl)-phenoxy]-butyric acid (ZD 2486)::CHEMBL118090::ZD-2486

SMILES C[C@@H](COc1ccc(cc1)N1CCN(CC1)c1ccncc1)CC(O)=O

InChI Key InChIKey=RVVTUJLHUHZYOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092099   

TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50092099(3-Methyl-4-[4-(4-pyridin-4-yl-piperazin-1-yl)-phen...)
Affinity DataIC50: 50nMAssay Description:Inhibition of glycoprotein IIb/III and platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50092099(3-Methyl-4-[4-(4-pyridin-4-yl-piperazin-1-yl)-phen...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed