BDBM50092625 3-[3-Iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)-benzyl]-5-phenyl-3,5-dihydro-1,3,5,6-tetraaza-cyclopenta[a]naphthalen-4-one::CHEMBL340379

SMILES: FC(F)(F)C1(N=N1)c1cc(I)cc(Cn2cnc3c2c(=O)n(-c2ccccc2)c2ncccc32)c1

InChI Key: InChIKey=RNMWWEZUYMOMIS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50092625 (3-[3-Iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)-b...) Show SMILES FC(F)(F)C1(N=N1)c1cc(I)cc(Cn2cnc3c2c(=O)n(-c2ccccc2)c2ncccc32)c1 Show InChI InChI=1S/C24H14F3IN6O/c25-24(26,27)23(31-32-23)15-9-14(10-16(28)11-15)12-33-13-30-19-18-7-4-8-29-21(18)34(22(35)20(19)33)17-5-2-1-3-6-17/h1-11,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4A expressed in Sf9 cells				J Med Chem 43: 3820-3 (2000) Article DOI: 10.1021/jm000065c BindingDB Entry DOI: 10.7270/Q23T9GG9
					More data for this Ligand-Target Pair