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BDBM50093314 4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-2-(4-methoxy-phenyl)-4H-benzo[1,4]oxazin-3-one::CHEMBL131448

SMILES: COc1ccc(cc1)C1Oc2ccccc2N(CCCCCN2C(C)CCCC2C)C1=O

InChI Key: InChIKey=IIVFKZRYVBKPLV-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093314   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50093314
PNG
(4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-2-(4-me...)
Show SMILES COc1ccc(cc1)C1Oc2ccccc2N(CCCCCN2C(C)CCCC2C)C1=O
Show InChI InChI=1/C27H36N2O3/c1-20-10-9-11-21(2)28(20)18-7-4-8-19-29-24-12-5-6-13-25(24)32-26(27(29)30)22-14-16-23(31-3)17-15-22/h5-6,12-17,20-21,26H,4,7-11,18-19H2,1-3H3
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MMDB

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Similars

Article
PubMed
n/an/a 4.90E+3n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
In vitro inhibition of coagulation factor Xa.


J Med Chem 43: 4063-70 (2000)


Article DOI: 10.1021/jm000074l
BindingDB Entry DOI: 10.7270/Q2W66K1H
More data for this
Ligand-Target Pair