BDBM50093753 (2S,3S)-2-Amino-3-benzyloxy-succinic acid::(2S,3S)-2-amino-3-(benzyloxy)succinic acid::(3S)-3-(BENZYLOXY)-L-ASPARTIC ACID::CHEMBL79140::DL-TBOA

SMILES N[C@@H]([C@H](OCc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=BYOBCYXURWDEDS-IUCAKERBSA-N

Data  3 KI  29 IC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50093753   

TargetGlutamate receptor 3(RAT)
Suntory Institute For Bioorganic Research

Curated by PDSP Ki Database
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Suntory Institute For Bioorganic Research

Curated by PDSP Ki Database
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
Suntory Institute For Bioorganic Research

Curated by PDSP Ki Database
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  1.61E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  6.37E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.30E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  1.61E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.21E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50: >1.00E+6nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  6.37E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  3.80E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.21E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  7.00E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of [14C]glutamate uptake at human EAAT3 expressed in african green monkey COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  960nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  955nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  3.72E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  6.40E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  2.10E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed