BDBM50093790 CHEMBL3585956

SMILES Cc1ncc(OC[C@]2(C[C@H]2C(=O)Nc2ccc(F)cn2)c2ccc(F)c(F)c2)c(C)n1

InChI Key InChIKey=DMXOPLLJONJSEU-KSFYIVLOSA-N

Data  2 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093790   

TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50093790(CHEMBL3585956)Copy SMILESCopy InChI

Affinity DataKi:  4nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50093790(CHEMBL3585956)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50093790(CHEMBL3585956)Copy SMILESCopy InChI

Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI