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BDBM50093797 Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl)-ethyl]-pyrrolidin-3-yl}-amide::CHEMBL84240

SMILES: O=C(NC1CCN(CCc2ccc(cc2)C#N)C1)C12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=CUOGJNWOVCPXJN-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093797   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50093797
PNG
(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Show SMILES O=C(NC1CCN(CCc2ccc(cc2)C#N)C1)C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C24H31N3O/c25-15-18-3-1-17(2-4-18)5-7-27-8-6-22(16-27)26-23(28)24-12-19-9-20(13-24)11-21(10-19)14-24/h1-4,19-22H,5-14,16H2,(H,26,28)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.5n/an/an/an/an/an/an/an/a



Welfide Corporation

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.


Bioorg Med Chem Lett 10: 2457-61 (2001)


Article DOI: 10.1016/s0960-894x(00)00492-3
BindingDB Entry DOI: 10.7270/Q2VT1SN2
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-1


(Homo sapiens (Human))
BDBM50093797
PNG
(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Show SMILES O=C(NC1CCN(CCc2ccc(cc2)C#N)C1)C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C24H31N3O/c25-15-18-3-1-17(2-4-18)5-7-27-8-6-22(16-27)26-23(28)24-12-19-9-20(13-24)11-21(10-19)14-24/h1-4,19-22H,5-14,16H2,(H,26,28)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
110n/an/an/an/an/an/an/an/a



Welfide Corporation

Curated by ChEMBL


Assay Description
Ability to displace [3H]-Prazosin binding to Alpha-1 adrenergic receptor


Bioorg Med Chem Lett 10: 2457-61 (2001)


Article DOI: 10.1016/s0960-894x(00)00492-3
BindingDB Entry DOI: 10.7270/Q2VT1SN2
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50093797
PNG
(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Show SMILES O=C(NC1CCN(CCc2ccc(cc2)C#N)C1)C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C24H31N3O/c25-15-18-3-1-17(2-4-18)5-7-27-8-6-22(16-27)26-23(28)24-12-19-9-20(13-24)11-21(10-19)14-24/h1-4,19-22H,5-14,16H2,(H,26,28)
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Welfide Corporation

Curated by ChEMBL


Assay Description
The compound was evaluated for the ability to displace [3H]- 8-OH -DPAT from 5-hydroxytryptamine 1A receptor ( striata of male wistar rats)


Bioorg Med Chem Lett 10: 2457-61 (2001)


Article DOI: 10.1016/s0960-894x(00)00492-3
BindingDB Entry DOI: 10.7270/Q2VT1SN2
More data for this
Ligand-Target Pair