BDBM50094076 CHEMBL434654::N-[4-(7-Chloro-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-3-methyl-phenyl]-2-o-tolyloxy-acetamide

SMILES Cc1ccccc1OCC(=O)Nc1ccc(C(=O)N2CCCCc3cc(Cl)ccc23)c(C)c1

InChI Key InChIKey=XCKIZAMEEBGGQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094076   

TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  0.950nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(RAT)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  5.10E+3nMAssay Description:Binding affinity of the compound towards rat Vasopressin V1a receptor after peroral administration of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  38nMAssay Description:Binding affinity of the compound towards rat Vasopressin V2 receptor after peroral administration of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed