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BDBM50094264 CHEMBL3589974

SMILES: Cc1ccccc1-c1noc(n1)-c1ccc(cc1)C(O)=O

InChI Key: InChIKey=JDKGUKAFQXKROH-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50094264   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bile acid receptor


(Homo sapiens (Human))
BDBM50094264
PNG
(CHEMBL3589974)
Show SMILES Cc1ccccc1-c1noc(n1)-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C16H12N2O3/c1-10-4-2-3-5-13(10)14-17-15(21-18-14)11-6-8-12(9-7-11)16(19)20/h2-9H,1H3,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 220n/an/an/an/a



Goethe-University Frankfurt

Curated by ChEMBL


Assay Description
Agonist activity at human full length FXR expressed in HeLa cells cotransfected with pSG5-human RXR after 24 hrs by Dual-Glo luciferase reporter gene...


Bioorg Med Chem 23: 3490-8 (2015)


Article DOI: 10.1016/j.bmc.2015.04.035
BindingDB Entry DOI: 10.7270/Q27M09PP
More data for this
Ligand-Target Pair