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BDBM50094844 (+/-)-2-Amino-6-methyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid::CHEMBL356502

SMILES: C[C@@]1([C@@H]2CC[C@](N)([C@H]12)C(O)=O)C(O)=O

InChI Key: InChIKey=WXRKAQKFVNVVIZ-QLKUOXBQSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094844   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50094844
PNG
((+/-)-2-Amino-6-methyl-bicyclo[3.1.0]hexane-2,6-di...)
Show SMILES C[C@@]1([C@@H]2CC[C@](N)([C@H]12)C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c1-8(6(11)12)4-2-3-9(10,5(4)8)7(13)14/h4-5H,2-3,10H2,1H3,(H,11,12)(H,13,14)/t4-,5+,8+,9+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formatio...


J Med Chem 43: 4893-909 (2000)


Article DOI: 10.1021/jm000346k
BindingDB Entry DOI: 10.7270/Q24J0DC8
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50094844
PNG
((+/-)-2-Amino-6-methyl-bicyclo[3.1.0]hexane-2,6-di...)
Show SMILES C[C@@]1([C@@H]2CC[C@](N)([C@H]12)C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c1-8(6(11)12)4-2-3-9(10,5(4)8)7(13)14/h4-5H,2-3,10H2,1H3,(H,11,12)(H,13,14)/t4-,5+,8+,9+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation


J Med Chem 43: 4893-909 (2000)


Article DOI: 10.1021/jm000346k
BindingDB Entry DOI: 10.7270/Q24J0DC8
More data for this
Ligand-Target Pair