BDBM50094884 CHEMBL3589154

SMILES COc1cc(ccc1OCC(C)(C)O)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

InChI Key InChIKey=GRPZZKMUWKOODM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094884   

TargetMelanin-concentrating hormone receptor 1(RAT)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50094884(CHEMBL3589154)
Affinity DataKi:  7.20nMAssay Description:Displacement of [125I][Phe13,Tyr19]-MCH from rat MCHR1 by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50094884(CHEMBL3589154)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-induced Ca2+ influx for 120 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50094884(CHEMBL3589154)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed