BDBM50095137 (3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid (5-{[(3S,4R)-4-(4-chloro-phenyl)-1-methyl-piperidine-3-carbonyl]-amino}-pentyl)-amide::3N-{5-[4-(4-chlorophenyl)-1-methyl-(3S,4R)-hexahydro-3-pyridinylcarboxamido]pentyl}-4-(4-chlorophenyl)-1-methyl-(3S,4R)-hexahydro-3-pyridinecarboxamide::CHEMBL41995
SMILES CN1CC[C@H]([C@@H](C1)C(=O)NCCCCCNC(=O)[C@@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1)c1ccc(Cl)cc1
InChI Key InChIKey=QVHOLGDTQLACOM-QUAHOIDUSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50095137
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of [3H]-5-HT uptake into rat synaptosomes by Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of high affinity serotonin uptake into rat synaptosomes using [3H]5-HTMore data for this Ligand-Target Pair
Affinity DataKi: 393nMAssay Description:Ability to inhibit high affinity uptake of norepinephrine transporter into the nerve endings of rat synaptosomes using [3H]NE as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 399nMAssay Description:Inhibition of norepinephrine transporter by inhibition of [3H]-NE uptake into rat nerve endings (synaptosomes)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.44E+3nMAssay Description:Displacement of [3H]mazindol binding to dopamine transporter (DAT) in rat synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.96E+3nMAssay Description:Inhibition of [3H]-DA uptake at Dopamine transporter into rat nerve endings (synaptosomes)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.96E+3nMAssay Description:Inhibition of high affinity DA uptake into rat synaptosomes using [3H]DAMore data for this Ligand-Target Pair