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BDBM50095140 CHEMBL3589516

SMILES: Cn1cc(CN2C[C@@H](CN(Cc3ccc(cc3)C#CC(C)(C)O)CC2=O)OCc2cccnc2)cn1

InChI Key: InChIKey=AXLBTHPTIVQLAP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095140   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inhibin beta A chain


(Mus musculus)
BDBM50095140
PNG
(CHEMBL3589516)
Show SMILES Cn1cc(CN2C[C@@H](CN(Cc3ccc(cc3)C#CC(C)(C)O)CC2=O)OCc2cccnc2)cn1
Show InChI InChI=1S/C15H11N3O3/c19-12(20)6-8-1-2-10-9(5-8)7-11-13(10)17-15(21)14-16-3-4-18(11)14/h1-5H,6-7H2,(H,17,21)(H,19,20)
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Similars

Article
PubMed
n/an/a 4.25E+3n/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Antagonist activity at activin A in mouse LbetaT2 cells transfected with -338 promoter region of FSHbeta gene conjugated to luciferase reporter asses...


J Med Chem 58: 5637-48 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00753
BindingDB Entry DOI: 10.7270/Q2RF5WSW
More data for this
Ligand-Target Pair