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BDBM50095141 CHEMBL3589517

SMILES: CCCn1ncc(CN2CCN(CCCc3ccccc3)[C@@H](CCO)C2)c1C

InChI Key: InChIKey=CRTNSWILELHMDV-QWVACARCNA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50095141   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inhibin beta A chain


(Mus musculus)
BDBM50095141
PNG
(CHEMBL3589517)
Show SMILES CCCn1ncc(CN2CCN(CCCc3ccccc3)[C@@H](CCO)C2)c1C
Show InChI InChI=1/C23H36N4O/c1-3-12-27-20(2)22(17-24-27)18-25-14-15-26(23(19-25)11-16-28)13-7-10-21-8-5-4-6-9-21/h4-6,8-9,17,23,28H,3,7,10-16,18-19H2,1-2H3/t23-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Antagonist activity at activin A in mouse LbetaT2 cells transfected with -338 promoter region of FSHbeta gene conjugated to luciferase reporter asses...


J Med Chem 58: 5637-48 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00753
BindingDB Entry DOI: 10.7270/Q2RF5WSW
More data for this
Ligand-Target Pair