BDBM50095261 (3-Chloro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-amine::4-(3'-chloroanilino)-6,7-diethoxyquinazoline hydrochloride::CHEMBL64950
SMILES CCOc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OCC
InChI Key InChIKey=VXCUTOVXETTYDM-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50095261
Affinity DataIC50: 1.60E+3nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for its concentration required to inhibit the rat liver F16BPaseMore data for this Ligand-Target Pair