BDBM50095356 CHEMBL3589028

SMILES CC(C)Cc1ccc(cc1)-c1[nH]ncc1CN(C)CCN

InChI Key InChIKey=KJHBJSSYYMWKLQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095356   

TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095356(CHEMBL3589028)
Affinity DataIC50:  5nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095356(CHEMBL3589028)
Affinity DataIC50:  10nMAssay Description:Inhibition of FLAG and hexa-histidine tagged full-length human PRMT6 expressed in HEK293F cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095356(CHEMBL3589028)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT8 expressed in Escherichia coli (BL21(DE3) pre-incubated for 30 mins before addition of a [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed