BDBM50095690 CHEMBL358289::N-(1-Cycloheptylmethyl-piperidin-4-yl)-2-(3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide

SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(CC2CCCCCC2)CC1)c1ccccc1

InChI Key InChIKey=ANXXZECPSLPAFT-GJZUVCINSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095690   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50095690(CHEMBL358289 | N-(1-Cycloheptylmethyl-piperidin-4-...)
Affinity DataKi:  28nMAssay Description:Ability to inhibit binding of [3H]-NMS was determined by receptor binding assay using membranes from chinese hamster ovary (CHO) cells expressing clo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50095690(CHEMBL358289 | N-(1-Cycloheptylmethyl-piperidin-4-...)
Affinity DataKi:  170nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50095690(CHEMBL358289 | N-(1-Cycloheptylmethyl-piperidin-4-...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed