BDBM50096647 2-(Biphenyl-4-yloxymethyl)-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-hydroxy-butyramide::CHEMBL101121

SMILES ONC(=O)C(CCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=VVZTYGQJDUUATC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50096647   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096647(2-(Biphenyl-4-yloxymethyl)-4-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096647(2-(Biphenyl-4-yloxymethyl)-4-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50:  768nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096647(2-(Biphenyl-4-yloxymethyl)-4-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096647(2-(Biphenyl-4-yloxymethyl)-4-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096647(2-(Biphenyl-4-yloxymethyl)-4-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed