BDBM50097565 CHEMBL3589947

SMILES COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccnc(F)c2)cc1

InChI Key InChIKey=ZNRCOWICXVSBFK-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097565   

TargetN-formyl peptide receptor 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50097565(CHEMBL3589947)
Affinity DataEC50:  660nMAssay Description:Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay in presence of probene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50097565(CHEMBL3589947)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human FPR2 transfected in human HL60 cells assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetFormyl peptide receptor-related sequence 1(Mouse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50097565(CHEMBL3589947)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at FPR2 in BALB/c mouse assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50097565(CHEMBL3589947)
Affinity DataEC50:  1.26E+4nMAssay Description:Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay in absence of probenec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed