BDBM50097882 CHEMBL3589842

SMILES Fc1cc(CNC(=O)CCCN2CCC3(CC2)OCCc2ccccc32)cc(c1)C(F)(F)F

InChI Key InChIKey=VCUDHYXMFJECKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097882   

TargetC-C chemokine receptor type 2(Mus musculus)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50097882(CHEMBL3589842)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity against mouse CCR2B expressed in human U2OS cells co-expressing beta-arrestin assessed as inhibition of mouse CCL2-induced beta-a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50097882(CHEMBL3589842)
Affinity DataIC50:  180nMAssay Description:Antagonist activity against human CCR2B expressed in Chem-1 cells assessed as inhibition of human CCL2-induced intracellular calcium flux incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed