BDBM50097892 CHEMBL3588870

SMILES COc1ccc2c(CCOC22CCN(CCC(C(=O)NCc3cc(cc(c3)C(F)(F)F)C(F)(F)F)c3ccc(F)cc3)CC2)c1

InChI Key InChIKey=ADRICAJEEHMWMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097892   

TargetC-C chemokine receptor type 2(Mus musculus)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50097892(CHEMBL3588870)
Affinity DataIC50:  4.16E+3nMAssay Description:Antagonist activity against mouse CCR2B expressed in human U2OS cells co-expressing beta-arrestin assessed as inhibition of mouse CCL2-induced beta-a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50097892(CHEMBL3588870)
Affinity DataIC50:  163nMAssay Description:Antagonist activity against human CCR2B expressed in Chem-1 cells assessed as inhibition of human CCL2-induced intracellular calcium flux incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed