BDBM50097895 CHEMBL355071::N-(5-Cyclopropyl-1-phenyl-1H-pyrazole-4-carbonyl)-guanidine

SMILES NC(=N)NC(=O)c1cnn(c1C1CC1)-c1ccccc1

InChI Key InChIKey=YZLNQKMWEXOAPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097895   

TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097895(CHEMBL355071 | N-(5-Cyclopropyl-1-phenyl-1H-pyrazo...)
Affinity DataIC50:  350nMAssay Description:In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097895(CHEMBL355071 | N-(5-Cyclopropyl-1-phenyl-1H-pyrazo...)
Affinity DataIC50:  1.28E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed