BDBM50098003 CHEMBL355301::N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylmethyl-acetamide

SMILES CCN(Cc1ccncc1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=PVWYVGHJHHUPFS-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50098003   

LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 20nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 43nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 47nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 54nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 65nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 106nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 190nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 250nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against human Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed