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BDBM50098089 4-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenoxy]-[1,4']bipiperidinyl-1'-carboxylic acid isopropyl ester::CHEMBL169876

SMILES: CC(C)OC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(cc1)S(=O)(=O)c1ccc2OCOc2c1

InChI Key: InChIKey=KXXFHCZMQSDTGH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098089   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50098089
PNG
(4-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenoxy]-[1,4'...)
Show SMILES CC(C)OC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(cc1)S(=O)(=O)c1ccc2OCOc2c1
Show InChI InChI=1S/C27H34N2O7S/c1-19(2)35-27(30)29-13-9-20(10-14-29)28-15-11-22(12-16-28)36-21-3-5-23(6-4-21)37(31,32)24-7-8-25-26(17-24)34-18-33-25/h3-8,17,19-20,22H,9-16,18H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.20n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards Muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand


Bioorg Med Chem Lett 11: 891-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00100-7
BindingDB Entry DOI: 10.7270/Q2SN087R
More data for this
Ligand-Target Pair