BDBM50098420 CHEMBL3593411

SMILES CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2ccnc(CNC(=O)C[C@H](OC1=O)\C=C\CCS)c2

InChI Key InChIKey=YSQNJKVHVWRCPW-FXHDEUNJSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098420   

TargetHistone deacetylase 1(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed