BDBM50098576 5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ACID ((S)-3-METHYL-1-{(S)-3-OXO-1-[2-(3-PYRIDIN-2-YLPHENYL)ACETYL]AZEPAN-4-YLCARBAMOYL}BUTYL)AMIDE::5-(2-Morpholin-4-yl-ethoxy)-benzofuran-2-carboxylic acid (3-methyl-1-{3-oxo-1-[2-(3-pyridin-2-yl-phenyl)-acetyl]-azepan-4-ylcarbamoyl}-butyl)-amide::CHEMBL284939
SMILES CC(C)C[C@H](NC(=O)c1cc2cc(OCCN3CCOCC3)ccc2o1)C(=O)N[C@H]1CCCN(CC1=O)C(=O)Cc1cccc(c1)-c1ccccn1
InChI Key InChIKey=KRMYDWCAHQJBOD-HEVIKAOCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50098576
Affinity DataKi: 0.00480nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibitory activity of the compound against Human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Inhibitory activity of the compound against Rat cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibitory activity of the compound against Human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibitory activity of the compound against Human cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human recombinant cathepsin S using Ac-KQLR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition of cathepsin S in human Raji cells assessed as decrease in cell surface expression of MHC class 2/CLIP by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro cell based assay for measuring the IC50 values of osteoblast resorption.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro IC50 value of the compound was measured using in situ cytochem assay.More data for this Ligand-Target Pair