BDBM50098775 3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (3-cyanomethyl-2,4,6-trimethyl-phenyl)-amide::CHEMBL279471

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)c(CC#N)c2C)c1C

InChI Key InChIKey=FMDCKBXKOAWRPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098775   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Texas Biotechnology

Curated by ChEMBL
LigandPNGBDBM50098775(3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-...)
Affinity DataIC50:  0.170nMAssay Description:Inhibitory concentration was determined against selective Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed