BDBM50099118 5-methyl-5-(4-phenoxyphenyl)barbituric acid::CHEMBL176467
SMILES CC1(C(=O)NC(=O)NC1=O)c1ccc(Oc2ccccc2)cc1
InChI Key InChIKey=RTBMLCLTYAPKIF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50099118
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 52nMAssay Description:In vitro binding affinity against matrix metalloprotease 9More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:In vitro binding affinity against matrix metalloprotease 13More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:In vitro binding affinity against matrix metalloprotease 2More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of human neutrophil collagenase-I, Matrix metalloproteinase-8More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of collagenase-3, Matrix metalloproteinase-13More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloproteinase-7More data for this Ligand-Target Pair