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BDBM50099318 CHEMBL13508::[(3S,4R)-4-(4-Chloro-phenyl)-1-phenyl-pyrrolidin-3-yl]-(2-methoxy-phenyl)-methanone

SMILES: COc1ccccc1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1)c1ccccc1

InChI Key: InChIKey=GLKLIRYNARPNEY-FCHUYYIVSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099318   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine transporters; Norepininephrine & dopamine


(Rattus norvegicus (rat))
BDBM50099318
PNG
(CHEMBL13508 | [(3S,4R)-4-(4-Chloro-phenyl)-1-pheny...)
Show SMILES COc1ccccc1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H22ClNO2/c1-28-23-10-6-5-9-20(23)24(27)22-16-26(19-7-3-2-4-8-19)15-21(22)17-11-13-18(25)14-12-17/h2-14,21-22H,15-16H2,1H3/t21-,22+/m0/s1
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.


Bioorg Med Chem Lett 11: 1113-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00132-9
BindingDB Entry DOI: 10.7270/Q24M952F
More data for this
Ligand-Target Pair